Spontaneous dissection of the superior mesenteric artery related to COVID-19
| Autor: | Leszek Kukulski, Gregor Scharf, Wilma Schierling, Karin Pfister, Birgit Linnemann |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Vasa. 52:107-118 |
| ISSN: | 1664-2872 0301-1526 |
| DOI: | 10.1024/0301-1526/a001051 |
| Popis: | Summary: Background: Spontaneous peripheral dissections are rare, and in a substantial number of cases, the underlying aetiology remains unclear. Patients and methods: We report the case of a 63-year-old male patient with a recent asymptomatic SARS-CoV-2 infection who presented with sudden-onset intermittent abdominal pain. Imaging studies revealed a dissection of the superior mesenteric artery (SMA) and large-vessel vasculitis involving the SMA as well as the carotid, subclavian, axillary and femoropopliteal arteries. In the absence of other predisposing factors, we supposed an association with prior COVID-19 and performed a systematic review of the literature to search for similar cases with arterial dissection related to acute or recent SARS-CoV-2 infection. Results: We identified 25 cases, including ours: 13 males and 12 females, with a median age of 48 years. In 22/25 patients, arterial dissection occurred within 4 weeks after the diagnosis of COVID-19 and involved the cerebral (11/25; 44%), coronary (10/25; 40%), splanchnic (3/25; 12%) and renal (2/25; 8%) arteries. Conclusions: Although initially known for its respiratory manifestations, it has become evident that SARS-CoV-2 not only infects pneumocytes but also enters the vascular endothelium, leading to endothelial dysfunction and hypercoagulability and – as shown in our case – large-vessel vasculitis, which may predispose patients to intramural haemorrhage and arterial dissection. |
| Databáze: | OpenAIRE |
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