Candida antarcticaLipase B (CAL-B)-Catalyzed Carbon-Sulfur Bond Addition and Controllable Selectivity in Organic Media

Autor:	De-Shui Lv, Bo-Kai Liu, Feng-Wen Lou, Xianfu Lin, Qi Wu
Rok vydání:	2008
Předmět:	inorganic chemicals biology Markovnikov's rule chemistry.chemical_element Regioselectivity General Chemistry biology.organism_classification Sulfur Enzyme catalysis Catalysis chemistry Organic chemistry lipids (amino acids peptides and proteins) Candida antarctica Selectivity Carbon
Zdroj:	Advanced Synthesis & Catalysis. 350:1959-1962
ISSN:	1615-4169 1615-4150
DOI:	10.1002/adsc.200800207
Popis:	A novel enzymatic, promiscuous protocol for Candida antarctica lipase B (CAL-B)-catalyzed carbon-sulfur bond addition is described. Some control experiments have been designed to demonstrate the catalytic specificity of CAL-B. Selectivity between anti-Markovnikov addition and Markovnikov addition was achieved in different organic media. A series of thioether-containing ester functional groups was synthesized under the catalysis of CAL-B at 50 °C. All the products were characterized by spectroscopic methods (IR, NMR, ESI-MS).
Databáze:	OpenAIRE
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