An Artemisinin Derivative ART1 Induces Ferroptosis by Targeting the HSD17B4 Protein Essential for Lipid Metabolism and Directly Inducing Lipid Peroxidation

Autor: Jie Xi, Zhiyuan Wang, Ge Chen, Ming Gao, Jidong Zhu, Xinxin Ma, Yu Yan, Hong-Dong Hao, Ze-Jun Xu, Jingjing Xie, Hui-Jun Chen, Zhu-Jun Yao, Guangya Zhu, Yaoyang Zhang
Rok vydání: 2022
Předmět:
Zdroj: CCS Chemistry. 4:304-317
ISSN: 2096-5745
DOI: 10.31635/ccschem.021.202000691
Popis: Artemisinin and its derivatives, commonly known as antimalarial drugs, have gradually come to be regarded as potential antitumor agents, although their cytotoxic efficacy and mechanisms of action r...
Databáze: OpenAIRE