An Artemisinin Derivative ART1 Induces Ferroptosis by Targeting the HSD17B4 Protein Essential for Lipid Metabolism and Directly Inducing Lipid Peroxidation

Autor:	Jie Xi, Zhiyuan Wang, Ge Chen, Ming Gao, Jidong Zhu, Xinxin Ma, Yu Yan, Hong-Dong Hao, Ze-Jun Xu, Jingjing Xie, Hui-Jun Chen, Zhu-Jun Yao, Guangya Zhu, Yaoyang Zhang
Rok vydání:	2022
Předmět:	Lipid peroxidation chemistry.chemical_compound Derivative (finance) Chemistry Ferroptosis parasitic diseases medicine Cytotoxic T cell Lipid metabolism General Chemistry Pharmacology Artemisinin medicine.drug
Zdroj:	CCS Chemistry. 4:304-317
ISSN:	2096-5745
Popis:	Artemisinin and its derivatives, commonly known as antimalarial drugs, have gradually come to be regarded as potential antitumor agents, although their cytotoxic efficacy and mechanisms of action r...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6eb9147bbfcd57e6d72d01c8d2685a93 https://doi.org/10.31635/ccschem.021.202000691 Zobrazit plný text záznamu