Protective properties of attenuated strains of the african swine fever virus in the course of immunodeficiency induced by radiation
| Autor: | V. A. Budarkov, A. D. Sereda, V. M. Balyshev |
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| Rok vydání: | 2017 |
| Předmět: |
African swine fever
Strain (chemistry) Inoculation 030231 tropical medicine Virulence Biology biology.organism_classification medicine.disease African swine fever virus Virology Virus 03 medical and health sciences Psychiatry and Mental health 0302 clinical medicine Neuropsychology and Physiological Psychology medicine 030212 general & internal medicine Immunodeficiency Cause of death |
| Zdroj: | Russian Agricultural Sciences. 43:432-436 |
| ISSN: | 1934-8037 1068-3674 |
| DOI: | 10.3103/s1068367417050044 |
| Popis: | Introduction of the FC-135 strain of an attenuated African swine fever (ASF) virus to immunodeficient swine did not cause clinical signs of the disease and protected them against the virulent strain France- 32. However, inoculation of an attenuated strain MC-200 was the cause of death from ASF of approximately half of animals with immunodeficiency and provided partial protection from further infection with the virulent strain Mozambique-78. Since reversions of virulent properties of the MC-200 strain have not been registered, the cause of death of pigs inoculated with the strain is the development of ASF against the background of immunodeficiency induced by radiation. |
| Databáze: | OpenAIRE |
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