| Autor: |
Dimitrios Zeugolis, James Phillips, Felicity Rose, Richard Oreffo, Simon Donell, Timothy Hardingham, Barrie Kellam, Deborah Mason, Colin Scotchford, Alexander Shard, Jonathan Campbell Knowles, Alexandra Stolzing, Kuo-Kang Liu, Tri Suciati, Vivek Mudera, Paul De Bank, Zhanfeng Cui, Carolina Stenfeldt, Hazel Screen, Wael Kafienah, Semali Perera, Steven Howdle, David Young, Helen Birch, Wilhelm K Aicher, Paul Hatton, Mark Lewis, Anthony Hayes, Jim Ralphs, David Geoffrey Spiller, Pierre Hardouin, Mark Ahearne, David Wilson, Jonny Blaker, Simon Tew, Keith Brennan, Adriaan Grobbelaar, Kevin Shakesheff, Ivan Martin, David Lee |
| Rok vydání: |
2005 |
| Předmět: |
|
| Zdroj: |
International Journal of Experimental Pathology. 86:A1-A56 |
| ISSN: |
0959-9673 |
| DOI: |
10.1111/j.0959-9673.2005.00426.x |
| Popis: |
of paper from TCES (Tissue and Cell Engineering Society) meeting in 2005. The ability of the skin to extend and recoil is mediated by an elastic fibre network comprising elastin molecules deposited on a microfibrillar scaffold. Studies have demonstrated reduced tensile strength in scar tissue following cutaneous wounding, possibly due to decreased amounts of elastic fibres1. The dermal component of artificial skin substitutes also lacks an organised elastic fibre network, which may contribute to excessive contraction and scarring post-grafting. This study aimed to document the temporal and spatial distribution of elastic fibres following incisional and excisional cutaneous wounding in mice. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Plný text