Gestörte Propriozeption bei amyotropher Lateralsklerose – Eine Studie mit Muskelvibration und transkranieller Magnetstimulation
| Autor: | Andon Kossev, C. Schrader, Jens D. Rollnik, S. Siggelkow |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Motor threshold
medicine.medical_specialty Muscle vibration Proprioception medicine.medical_treatment Audiology Stimulus (physiology) medicine.disease Riluzole Transcranial magnetic stimulation Physiology (medical) Anesthesia medicine Intracortical inhibition Neurology (clinical) Amyotrophic lateral sclerosis Psychology medicine.drug |
| Zdroj: | Klinische Neurophysiologie. 39:262-266 |
| ISSN: | 1439-4081 1434-0275 |
| Popis: | The processing of proprioception in amyotrophic lateral sclerosis (ALS) patients was studied with paired-pulse transcranial magnetic stimulation (TMS) and muscle vibration (MV). 13 ALS patients (7 with riluzole, 6 without riluzole) and 10 age-matched healthy controls were enrolled into this study. Paired-pulse TMS was carried out with interstimulus-intervals of 3 ms to test for intracortical inhibition (ICI), and 13 ms to test for intracortical facilitation (ICF); intensity of the conditioning stimulus was 70% (test stimulus 120%) of motor threshold. ALS patients without riluzole showed an impairment of ICI (p |
| Databáze: | OpenAIRE |
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