Quercetin nanocrystals prepared by a novel technique improve the dissolution rate and antifibrotic activity of quercetin

Autor:	Pegah Cheshmehnoor, Shahram Rabbani, Azadeh Haeri
Rok vydání:	2023
Předmět:	Biomedical Engineering Medicine (miscellaneous) General Materials Science Bioengineering Development
Zdroj:	Nanomedicine. 18:89-107
ISSN:	1748-6963 1743-5889
DOI:	10.2217/nnm-2022-0032
Popis:	Aim: To develop quercetin nanocrystals by a simple approach and to evaluate their in vivo antifibrotic efficacy. Materials & methods: Nanosuspensions were fabricated by a thin-film hydration technique and ultrasonication. The influence of process variables on the average diameter of quercetin nanoparticles was investigated. Moreover, in vivo efficacy was investigated in an established murine CCl4-induced fibrosis model. Results: Nanocrystals showed a particle size of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6e9ec76a0788e9d882b668491030a12b https://doi.org/10.2217/nnm-2022-0032 Zobrazit plný text záznamu