Synthesis and characterization of new biologically active palladium(II) complexes with (1E,6E)-1,7-bis(3,4-diethoxyphenyl)-1,6-heptadiene-3,5-dione
Autor: | Jindra Valentová, Ferdinand Devínsky, Lenka Kucková, Olga Soritau, Eva Fischer-Fodor, Roman Mikláš, Natalia Miklášová, Jozef Kožíšek, Tibor Liptaj |
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Rok vydání: | 2014 |
Předmět: | |
Zdroj: | Inorganic Chemistry Communications. 46:229-233 |
ISSN: | 1387-7003 |
DOI: | 10.1016/j.inoche.2014.06.006 |
Popis: | Two new palladium complexes with (1E,6E)-1,7-bis(3,4-diethoxyphenyl)-1,6-heptadiene-3,5-dione, 1 and 2, have been synthesized and structurally characterized. Complex 1 has the molecular structure confirmed by X-ray diffraction measurements. Both complexes display a significant antiproliferative activity against human colorectal cancer cells by inducing early and late apoptotic processes in those cells. |
Databáze: | OpenAIRE |
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