Intramolecular cyclization of aryl substituted iodonium ylides with copper(I) chloride

Autor:	Eric J. May, Om Prakash, Robert M. Moriarty
Rok vydání:	1997
Předmět:	chemistry.chemical_compound chemistry Aryl Yield (chemistry) Organic Chemistry Drug Discovery Intramolecular cyclization Copper(I) chloride Biochemistry Medicinal chemistry Decomposition
Zdroj:	Tetrahedron Letters. 38:4333-4336
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(97)00967-2
Popis:	Cu(I)Cl decomposition of the phenyliodonium ylides derived from o-, m- and p-methoxyphenyl-3-ketopentanoic acid methyl esters affords the corresponding 5-, 6- and 7-methoxy-1-carbomethoxy-2-tetralones in preparative yields. The lower homologous phenyliodonium ylides derived from o-, m- and p-methoxyphenyl-3-ketobutyric acid methyl esters yield the analogous 1-carbomethoxy-2-indanone only in the meta-methoxyphenyl case, and the ortho- and para-methoxyphenyl substituted iodonium ylides yield dimeric products.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6e6c02492793654c8b98141065dabd5a https://doi.org/10.1016/s0040-4039(97)00967-2 Zobrazit plný text záznamu Full Text from ScienceDirect