Some immunochemical properties of natural antiglobulin factors (homoreactants)

Autor:	S. Yusupova-Redai, A. Ya. Kul'berg, Yu. P. Reznikov, Bartova Lm
Rok vydání:	1975
Předmět:	medicine.anatomical_structure Human blood Antigen Sephadex Effector Chemistry Placenta Homologous chromosome medicine General Medicine Normal pregnancy Molecular biology General Biochemistry Genetics and Molecular Biology
Zdroj:	Bulletin of Experimental Biology and Medicine. 80:796-798
ISSN:	1573-8221 0007-4888
Popis:	A naturally occurring antiglobulin factor against the Fab-fragment of homologous IgG, contained in the rabbit and human blood serum and γ-globulin preparations, was shown by gelfiltration on Sephadex G-200 to have a molecular weight of about 250,000 daltons. In man this factor does not pass through the placenta in normal pregnancy. Despite differences in the physicochemical and effector properties of 7S IgG and protein with homoreactant activity, the latter has the specific antigenic determinants of IgG. These observations suggest that a complex of IgG with another protein or nonprotein compound possesses homoreactant properties.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6e680bcb0fbde8b0e1835070c9f86768 https://doi.org/10.1007/bf00809894 Zobrazit plný text záznamu Full text from SpringerLink