Antibiotic susceptibility pattern and risk factors associated with Acinetobacter and Pseudomonas infection at a tertiary care hospital
| Autor: | Jatan Bahadur Sherchan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
biology Pseudomonas aeruginosa medicine.drug_class business.industry Antibiotics Acinetobacter medicine.disease_cause biology.organism_classification medicine.disease Multiple drug resistance Antibiotic resistance Pseudomonas infection Internal medicine medicine business Bacteria Susceptibility pattern |
| Zdroj: | Journal of Kathmandu Medical College. 10:4-10 |
| ISSN: | 2091-1793 2091-1785 |
| DOI: | 10.3126/jkmc.v10i1.38945 |
| Popis: | Background: Infection due to Acinetobacter spp. and Pseudomonas aeruginosa is a major worldwide concern these days. Antibiotic resistance and predisposing factors among the patients for acquiring such infection is a major challenge globally and in Nepal. Objectives: To determine antimicrobial susceptibility pattern of Acinetobacter spp. and Pseudomonas aeruginosa isolates along with predisposing factors. Methods: A total of 9,705 clinical samples were processed in this analytical cross-sectional study from December 2019 to November 2020. Antibiotic susceptibility pattern was determined following Clinical Laboratory Standard Institute guidelines. Patients’ information was obtained after informed consent. Results: Acinetobacter spp. and Pseudomonas aeruginosa isolates were 92 (0.95%). Fifty-three (57.61%) samples were respiratory samples. Thirteen (20%) Pseudomonas aeruginosa and 18 (66.67%) Acinetobacter spp. were multidrug-resistant (MDR). Eight (12.31%) Pseudomonas aeruginosa strains and 13 (48.15%) Acinetobacter spp. strains were sensitive only to Colistin. Twenty-two (95.65%) prolonged hospital stayers had MDR bacteria compared to only nine (13.04%) non-prolonged hospital stayers (p-value |
| Databáze: | OpenAIRE |
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