Effects of methyluracil and hydroxymethacil on free-radical oxidation in model systems
| Autor: | V. A. Myshkin, D. A. Enikeev, V. P. Krivonogov, Z. G. Khaibullina, S. A. Bashkatov |
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| Rok vydání: | 1995 |
| Předmět: |
chemistry.chemical_classification
Antioxidant Pyrimidine medicine.medical_treatment Salt (chemistry) chemistry.chemical_element General Medicine General Biochemistry Genetics and Molecular Biology Lipid peroxidation chemistry.chemical_compound chemistry Free radical oxidation medicine Organic chemistry Lithium |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 120:785-788 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | Three pyrimidine derivatives — methyluracil, hydroxymethacil (a new compound), and its lithium salt — were tested in model systems of differing complexity for antioxidant properties in comparison with the well-known antioxidant ionol. Tests for antiradical activity and for effects on spontaneous and Fe2+-ascorbate- or NADPH-dependent lipid peroxidation revealed high antioxidant activity (comparable to that of ionol) of the hydroxymethacil lithium salt. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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