Role of Vitamins in Biotransformation of Xenobiotics
Autor: | P. I. Lukienko, M. I. Bushma, L. I. Sushko |
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Rok vydání: | 1985 |
Předmět: | |
Zdroj: | Archives of Toxicology ISBN: 9783540136705 |
DOI: | 10.1007/978-3-642-69928-3_79 |
Popis: | Many toxic substances and drugs are oxidated in the cytochrome P-450-dependent monooxygenase system of the rat liver endoplasmic reticulum. To elucidate a role of vitamins in this system activity a study was made of the change in the cytochrome P-450 content, electron transport in the NADPH- and NADH-dependent redox chains and the rates of aniline and amidopyrine catabolism in rat liver microsomes. |
Databáze: | OpenAIRE |
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