Role of Vitamins in Biotransformation of Xenobiotics

Autor: P. I. Lukienko, M. I. Bushma, L. I. Sushko
Rok vydání: 1985
Předmět:
Zdroj: Archives of Toxicology ISBN: 9783540136705
DOI: 10.1007/978-3-642-69928-3_79
Popis: Many toxic substances and drugs are oxidated in the cytochrome P-450-dependent monooxygenase system of the rat liver endoplasmic reticulum. To elucidate a role of vitamins in this system activity a study was made of the change in the cytochrome P-450 content, electron transport in the NADPH- and NADH-dependent redox chains and the rates of aniline and amidopyrine catabolism in rat liver microsomes.
Databáze: OpenAIRE