Size and Duration of Zidovudine Benefit in 1003 HIV-Infected Patients: U.S. Army, Navy, and Air Force Natural History Data
| Autor: | David L. Cohn, Raymond C.-Y. Chung, Richard W. Harris, Shannon H. Harrison, Lytt I. Gardner, Stephen P. Blatt, Douglas L. Mayers, Craig W. Hendrix, Kenneth F. Wagner, Donald S. Burke |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
biology business.industry Immunology virus diseases medicine.disease biology.organism_classification Confidence interval Surgery Zidovudine Acquired immunodeficiency syndrome (AIDS) Virology Relative risk Immunopathology Internal medicine Epidemiology Immunology and Allergy Medicine business Sida Cohort study medicine.drug |
| Zdroj: | Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 17:345-353 |
| ISSN: | 1077-9450 |
| Popis: | Objectives: The study's objectives were to determine the size and duration of benefits of early versus delayed versus late treatment with zidovudine (ZDV) on disease progression and mortality in HIV-infected patients, and whether patients rapidly progressing before ZDV treatment had a different outcome from those not rapidly progressing before ZDV. Design: The design was an inception cohort of 1003 HIV-infected patients. One hundred and seventy-four of the 1003 patients were treated before CD4 counts fell to < 400 x 109/L, ('early treatment'); 183 of 1003 patients were treated after CD4 counts fell to |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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