Synthesis of 5-(4-nitrophenyl)-2-aminopyrazine

Autor: Wu Fu Zhu, Chun Jiang Wu, Le Chen, Peng Wu Zheng, Shan Xu, Hui Xia, Wenhui Wang, Min Wang
Rok vydání: 2014
Předmět:
Zdroj: Advanced Materials Research. 1081:67-70
ISSN: 1662-8985
DOI: 10.4028/www.scientific.net/amr.1081.67
Popis: 5-(4-nitrophenyl)-2-aminopyrazine (13) was synthesized from 2-aminopyrazine (9) through two steps including monobrominated reaction, Suzuki-Miyaura coupling and the structures were confirmed by 1H NMR and MS spectrum. The synthetic method of 13 was optimized and can be used to synthesize 5-(4-nitrophenyl)-2-aminopyrazine derivatives.
Databáze: OpenAIRE