SPECT and SPECT/CT

Autor: Freek J. Beekman, Brian Hutton, Marlies C Goorden
Rok vydání: 2021
Předmět:
DOI: 10.1016/b978-0-12-816386-3.00008-9
Popis: Single photon emission computed tomography (SPECT) and SPECT-CT are widely used in clinical practice, mostly based on rotation of planar gamma cameras. Tomographic images are reconstructed mainly using iterative algorithms that permit use of flexible geometry and can easily incorporate various corrections. There are several recent advances in instrumentation that include the use of solid state detectors and specialized collimators with improved performance in terms of spatial resolution and/or energy resolution. Compact systems can be constructed that are well suited to organ-specific application with advantages over conventional rotating cameras. With appropriate correction for attenuation and scatter, as well as the effects of motion and limited resolution, absolute quantification of activity concentration is possible. This is particularly important in the increasingly important area of theranostics where radiation dose to target organs or tissues at risk can be estimated.
Databáze: OpenAIRE