Improved Synthesis of Prostanoids on a Non-Cross-Linked Polystyrene Soluble Support

Autor: Sheng-Yuh Tang, Raffaella Manzotti, Kim D. Janda
Rok vydání: 2000
Předmět:
Zdroj: Tetrahedron. 56:7885-7892
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(00)00707-9
Popis: Prostaglandins are potent natural products which are involved in many biological processes. Here we report an improved synthesis of prostanoids by a three-component coupling approach using a soluble-polymer supported technique. Access to prostanoids should be valuable in drug discovery programs.
Databáze: OpenAIRE