Conceptual design of an RFQ accelerator-based neutron source for boron neutron-capture therapy

Autor: T.S. Bhatia, T. E. Blue, C. K. Wang, J. E. Stovall, R. A. Gahbauer, T.P. Wangler
Rok vydání: 2003
Předmět:
Zdroj: Proceedings of the 1989 IEEE Particle Accelerator Conference, . 'Accelerator Science and Technology.
Popis: A conceptual design of a low-energy neutron generator for treatment of brain tumors by boron neutron capture therapy (BNCT) is presented. The concept is based on a 2.5-MeV proton beam from a radio-frequency quadrupole (RFQ) linac, and the neutrons are produced by the /sup 7/Li(p,n)/sup 7/Be reaction. A liquid lithium target and modulator assembly are designed to provide a high flux of epithermal neutrons. The patient is administered a tumor-specific /sup 10/B-enriched compound and is irradiated by the neutrons to create a highly located dose from the reaction /sup 10/B(n, alpha )/sup 7/Li. An RFQ accelerator-based neutron source for BNCT is compact, which makes it practical to site the facility within a hospital. >
Databáze: OpenAIRE