Oxidative NHC catalysis: direct activation of β sp3 carbons of saturated acid chlorides
| Autor: | Qing-Wei Ma, Dou Liu, Shi-Ya Zhu, Hua Zhang, Xin-Ping Hui |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Metals and Alloys
chemistry.chemical_element General Chemistry Oxidative phosphorylation Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound chemistry Yield (chemistry) Electrophile Materials Chemistry Ceramics and Composites Organic chemistry Stereoselectivity Carbene Carbon |
| Zdroj: | Chemical Communications. 55:298-301 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c8cc08578a |
| Popis: | The first activation of saturated acid chlorides by oxidative N-heterocyclic carbene catalysis has been successfully utilized to synthesize enantio-enriched spirooxindole lactones and δ-lactones. The reaction involves the transformation of the β sp3 carbon of saturated acid chlorides into an electrophilic carbon as a key step. The product was obtained in excellent yield and stereoselectivity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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