| Autor: |
Gabriella Liszkay, Angela Benedek, Csaba Polgár, Judit Oláh, Péter Holló, Gabriella Emri, András Csejtei, István Kenessey, Zoltán Polányi, Kata Knollmajer, Máté Várnai, Zoltán Vokó, Balázs Nagy, György Rokszin, Ibolya Fábián, Zsófia Barcza, Rolland Gyulai, Zoltan Kiss |
| Rok vydání: |
2022 |
| ISSN: |
2015-2019 |
| DOI: |
10.1101/2022.04.06.22273390 |
| Popis: |
BackgroundRecent real-world studies have reported significant improvements in the survival of malignant melanoma in the past few years, mainly as a result of modern therapies. However, long-term survival data from Central Eastern European countries such as Hungary are currently lacking.MethodsThis nationwide, retrospective study examined melanoma survival in Hungary between 2011–2019 using the databases of the National Health Insurance Fund (NHIF) and Central Statistical Office (CSO) of Hungary. Crude overall survival and age-standardized 5-year net survival as well as the association between age, sex, and survival were calculated.ResultsBetween 2011 and 2019, 22,948 newly diagnosed malignant melanoma cases were recorded in the NHIF database (47.89% male, mean age: 60.75 years (SD: ±16.39)). 5-year overall survival was 75.40% (women: 80.78%; men: 69.52%). Patients diagnosed between 2017–2019 had a 20% lower risk of mortality compared to patients diagnosed between 2011–2012 (HR 0.80, 95% CI 0.73–0.89; pConclusionHungary has similar melanoma survival rates to Western European countries. Based on net survival, the risk of dying of melanoma within 5 years was cut by more than half (55%) during the study period, which coincides with the successful implementation of awareness campaigns and the wide availability of modern therapies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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