Oberflächenanästhesie des Trommelfells mit DMSO und Lokalanästhetika*

Autor:	R. E. Blessing, Schlenter Ww
Rok vydání:	1990
Předmět:	Tetracaine Chemistry Dimethyl sulfoxide medicine.medical_treatment Myringotomy chemistry.chemical_compound Membrane Topical anesthesia medicine.anatomical_structure Otorhinolaryngology Anesthesia medicine Cocaine hydrochloride Grommet Eardrum medicine.drug
Zdroj:	Laryngo-Rhino-Otologie. 69:285-288
ISSN:	1438-8685 0935-8943
DOI:	10.1055/s-2007-998191
Popis:	A solution of 10% cocaine hydrochloride plus 10% water in 80% dimethyl sulfoxide (DMSO) or 5% tetracaine base in pure DMSO was topically applied to the eardrum in 112 and 52 cases respectively. Both preparations induced well-tolerated analgesia suitable for myringotomy with or without insertion of a grommet in the office environment. DMSO-tetracaine induced analgesia within ten, DMSO-cocaine within 30 minutes. This method has distinct advantages as compared to iontophoretically induced analgesia or topical agents with a destructive mode of action.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6dd8a2bc5090f37e54f60e1fa5f38d8f https://doi.org/10.1055/s-2007-998191 Zobrazit plný text záznamu