ChemInform Abstract: Cinchona Alkaloid Squaramide/AgOAc Cooperatively Catalyzed Diastereo- and Enantioselective Mannich/Cyclization Cascade Reaction of Isocyanoacetates and Cyclic Trifluoromethyl Ketimines

Autor: Hong-Lei Bi, Mei-Xin Zhao, Min Shi, Rong-Hui Jiang, Xu-Wei Xu
Rok vydání: 2015
Předmět:
Zdroj: ChemInform. 46
ISSN: 0931-7597
DOI: 10.1002/chin.201510221
Popis: A highly diastereo- and enantioselective Mannich cyclization cascade reaction of trifluoromethyl-substituted cyclic ketimines and α-aryl isocyanoacetates is developed using a multi-hydrogen-bonding squaramide combined with AgOAc as the catalyst.
Databáze: OpenAIRE