Could sST2 Predict Contrast-Induced Nephropathy in ST-Segment Elevation Myocardial Infarction?
| Autor: | Murat Can, Ahmet Avcı, Mustafa Umut Somuncu, Ferit Akgül |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry Contrast-induced nephropathy General Medicine 030204 cardiovascular system & hematology medicine.disease Logistic regression Gastroenterology Nephropathy 03 medical and health sciences 0302 clinical medicine Blood pressure 030220 oncology & carcinogenesis Diabetes mellitus Internal medicine medicine ST segment Medical history Myocardial infarction business |
| Zdroj: | International Journal of General Medicine. 13:1297-1304 |
| ISSN: | 1178-7074 |
| DOI: | 10.2147/ijgm.s287834 |
| Popis: | Background and Aim One of the most worrying complications of primary percutaneous coronary interventions is contrast-induced nephropathy (CIN) that is associated with increased mortality and morbidity in myocardial infarction. In this study, we questioned whether soluble suppression of tumorigenesis-2 (sST2), which has thought to play a role in inflammatory processes, cardiac remodeling, and fibrosis could give an idea about the development of CIN in ST-elevation myocardial infarction (STEMI) patients. Patients and Methods This study is a cross-sectional observational study and includes 357 consecutive STEMI patients. Demographic features, medical history, laboratory parameters, and procedural characteristics were compared according to CIN's development. The multivariate logistic regression analysis was selected to detect independent risk factors of CIN. Results In the study, 81 patients (22.7%) who developed CIN were identified. The concentration of sST2 in CIN (+) group was higher than that of CIN (-) group (40.6±21.0 ng/mL vs 31.5±13.0 ng/L, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|