Studies on the Synaptic Function in Muscle after Nerve Crush in Normal and Diabetic Rats
Autor: | R. Siliprandi, H. Ladinsky, Alfredo Gorio, R. Zanoni, F. Di Gregorio, C. Scozzesi, S. Consolo |
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Rok vydání: | 1986 |
Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases business.industry nutritional and metabolic diseases Streptozotocin medicine.disease Nerve conduction velocity Peripheral Extensor digitorum longus muscle Synaptic function chemistry.chemical_compound Endocrinology chemistry Internal medicine Alloxan Diabetes mellitus Nerve crush Medicine business medicine.drug |
Zdroj: | Advances in Behavioral Biology ISBN: 9781468451962 |
DOI: | 10.1007/978-1-4684-5194-8_34 |
Popis: | Spontaneous diabetes can develop a neuropathy that affects function and morphology of the peripheral nerves both in men and in animals (7, 14, 16, 22). Diabetes can also be induced by a single injection of Alloxan or Streptozotocin (15), drugs that exert a toxic effect on the beta-cells of the Langerhans islets. In rats treated with either. Alloxan or Streptozotocin a decrease in nerve conduction velocity is evident within a few weeks after intoxication (3, 20). |
Databáze: | OpenAIRE |
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