| Popis: |
Positron emission tomography (PET) provides an advanced imaging technology that permits the accurate definition of regional tracer distribution. In combination with nitrogen-13 (N-13) ammonia, PET allows for the sensitive and specific detection of coronary artery disease. Several studies indicate the superiority of this approach in comparison to standard thallium-201 (Tl-201) tomographic (SPECT) imaging. In addition, regional blood flow can be accurately measured using N-13 ammonia PET, and this approach can be employed in conjunction with pharmacologic stress imaging to quantify regional flow reserve. In combination with metabolic markers, N-13 ammonia is capable of assessing myocardial viability. Furthermore, the N-13 ammonia PET approach may differentiate between various forms of cardiomyopathy. More studies are needed to define the cost-benefit ratio of the N-13 ammonia PET technique for the management of patients with coronary artery disease or cardiomyopathy. |
