ChemInform Abstract: Novel Thiophene-, Pyrrole-, Furan-, and Benzenecarboxamidotetrazoles as Potential Antiallergy Agents

Autor:	M. C. Conroy, John A. Kennedy, David Orel Thueson, David T. Connor, Roderick Joseph Sorenson, M. D. Mullican
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry Furan Thiophene Organic chemistry General Medicine Antiallergy Agents Histamine Pyrrole
Zdroj:	ChemInform. 22
ISSN:	0931-7597
DOI:	10.1002/chin.199152186
Popis:	The synthesis and antiallergic activity of a series of novel thiophene-, pyrrole-, furan-, and benzenecarboxamidotetrazoles are described. A number of compounds inhibit the release of histamine from anti-IgE-stimulated human basophils. Optimal inhibition is exhibited in compounds with a 3-alkoxy, a 4-halo, and a 5-methyl, 5-methoxy, or 5-bromo on a thiophene-2-carboxamidotetrazole.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6db6c8bdcefefcbf2720ca4dc997d0ad https://doi.org/10.1002/chin.199152186 Zobrazit plný text záznamu Plný text