Localisations extrathoraciques graves de la sarcoïdose
| Autor: | C. Chapelon Abric |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Chemotherapy
Systemic disease medicine.medical_specialty Pathology Cyclophosphamide business.industry Urinary system medicine.medical_treatment Gastroenterology medicine.disease Dermatology Immunosuppressive drug Internal Medicine medicine Methotrexate Sarcoidosis Differential diagnosis business medicine.drug |
| Zdroj: | La Revue de Médecine Interne. 32:80-85 |
| ISSN: | 0248-8663 |
| DOI: | 10.1016/j.revmed.2010.08.024 |
| Popis: | Sarcoidosis may affect functional outcome and sometimes may be a life-threatening condition. Functional outcome is particularly compromised by cutaneous, ocular, nasal, osteoarticular manifestations and some neurological expression. Central nervous system involvement and cardiac sarcoidosis could be life-threatening, as laryngeal and renal involvement. Diagnosis is sometimes very difficult to obtain. Several tissue biopsies are usually necessary to rule out all differential diagnosis. Extrathoracic manifestations of severe sarcoidosis require a corticosteroid therapy, initiated, if life-threatening at a daily dose of 1 mg/kg, usually associated with an other immunosuppressive drug (methotrexate, cyclophosphamide, anti TNFα). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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