| Popis: |
Background. This study aims to examine the validity of European quality of life-5 dimensions, 3-level version (EQ-5D-3L) on patients with osteoporotic vertebral fractures and compare health related quality of life (QOL) of these patients with them of general population in Korea. Methods. Totally, 163 patients with osteoporotic fractures in any vertebrae from outpatient clinics of multiple hospitals. After informed consents, study participants administered general and clinical information including sex, age, fracture site, and fracture age. Then they filled up several questionnaires such as EQ-5D-3L, 12-item short form health survey version 2.0 (SF-12v2), Roland-Morris disability questionnaire (RMQ) and Pain numeric rating scale (PAIN NRS). To examine the discriminant and convergent validity of EQ-5D-3L, Spearman's correlation analyses among the questionnaires were conducted. Also, PAIN NRS, physical component summary (PCS) and mental component summary (MCS) from SF-12v2 and RMQ scores were compared on problems reporting of each dimension of EQ-5D-3L. Finally, results in EQ-5D-3L from study participants were compared with those things from the comparison group of general populations which were match-sampled according to age and sex from the 2013 Korean National Health and Nutritional Examination Survey. Results. Spearman's correlation coefficients among EQ-5D-3L and PAIN NRS, SF-12v2, and RMQ were mostly statistically significant. The coefficients between the relevant dimensions such as mobility of EQ-5D-3L and physical functioning of SF-12v2were higher than coefficients between the irrelevant ones. Study participants reporting problems in each dimension of EQ-5D-3L showed lower scores on PAIN NRS, PCS and MCS from SF-12v2 and RMQ scores and those were statistically significant. For comparisons with the general populations, problems reporting in the patient group were statistically higher than those things from the general people. Conclusions. This study showed that EQ-5D-3L could be valid to measure a health related QOL of patients with osteoporotic vertebral fractures in Korea. |
