New insights into the exercise intolerance of β-thalassemia major patients
| Autor: | V. Ladis, Serafeim Nanas, Dimitrios Sakellariou, Athanasios Tasoulis, S. Kapsimalakou, A. Aessopos, Stavros Dimopoulos, Ioannis Vasileiadis, Ourania Papazachou, G. Pangalis |
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| Rok vydání: | 2008 |
| Předmět: |
Spirometry
medicine.medical_specialty medicine.diagnostic_test business.industry chemistry.chemical_element VO2 max Physical Therapy Sports Therapy and Rehabilitation Cardiopulmonary exercise testing Exercise intolerance BETA THALASSEMIA MAJOR Oxygen Surgery chemistry Internal medicine Breathing Cardiology Medicine Orthopedics and Sports Medicine medicine.symptom business Anaerobic exercise |
| Zdroj: | Scandinavian Journal of Medicine & Science in Sports. 19:96-102 |
| ISSN: | 0905-7188 |
| DOI: | 10.1111/j.1600-0838.2008.00778.x |
| Popis: | The purpose of our study was assessment of the relative contribution of the systems involved in blood gas exchange to the limited exercise capacity in patients with beta-thalassemia major (TM) using integrative cardiopulmonary exercise testing (CPET) with estimation of oxygen kinetics. The study consisted of 15 consecutive TM patients and 15 matched controls who performed spirometric evaluation, measurement of maximum inspiratory pressure (Pimax) and an incremental symptom-limited CPET on a cycle ergometer. Exercise capacity was markedly reduced in TM patients as assessed by peak oxygen uptake (pVO(2), mL/kg/min: 22.1+/-6.6 vs 33.8+/-8.3; P |
| Databáze: | OpenAIRE |
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