Relationship between cord blood vitamin D level and group B Streptococcus vaginal carriage rate in pregnant women
| Autor: | Hugues Patural, Georges Teyssier, Mohamad Mteirek, Beatrice Trombert-Paviot, Denise Chhin, M.-N. Varlet, Roxana Diehl, Philippe Goffaux, Bruno Pozzetto |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Pregnancy Nutrition and Dietetics business.industry Obstetrics Endocrinology Diabetes and Metabolism Venous blood medicine.disease Group B Neonatal infection Carriage Cord blood Vitamin D and neurology Medicine Antibiotic prophylaxis business reproductive and urinary physiology |
| Zdroj: | e-SPEN Journal. 8:e150-e154 |
| ISSN: | 2212-8263 |
| Popis: | summary Background & aims: Group B streptococci (GBS) are a major cause of neonatal infection. The existence of a link between levels of vitamin D and vaginal carriage of GBS was investigated. Methods: Vitamin D level, assayed from umbilical venous blood at birth, and the status of GBS vaginal carriage during the last term of pregnancy were available from 2246 motherechild couples. Results: Levels of vitamin D in cord blood at birth was deficient ( 30 ng/ml) in 32.1%, 53.0% and 14.9% of tested subjects, respectively. Levels differed significantly depending on the season of delivery, the duration of exposure to sunlight, the skin phototype, and on vitamin D supplementation. The percentage of GBS vaginal carriage was 15.4. A negative association was observed between GBS vaginal carriage and level of vitamin D (P < 0.01 by chi-square test). No relationship was established between GBS colonisation (27 cases identified) or infection (7 cases identified) and vitamin D status. Conclusions: A correct vitamin D level was associated with a lower rate of GBS vaginal carriage during pregnancy. This calls for the monitoring of vitamin D status in pregnant women, a screen which could greatly reduce the need for intrapartum antibiotic prophylaxis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect