α-Hydroxylation of ketones: Osmium tetroxide/N-methylmorpholine-N-oxide oxidation of silyl enol ethers

Autor:	Witold Tomasik, Mark W. Johnson, J.P. McCormick
Rok vydání:	1981
Předmět:	chemistry.chemical_compound Silylation Osmium tetroxide Chemistry Organic Chemistry Drug Discovery N-Methylmorpholine N-oxide Organic chemistry α hydroxylation Biochemistry Enol
Zdroj:	Tetrahedron Letters. 22:607-610
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(01)92501-8
Popis:	Osmium tetroxide/N-methylmorpholine-N-oxide oxidation of silyl enol ethers, derived from ketones with either kinetic or thermodynamic regiochemical control, produces α-ketols in good to excellent yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6d472ec2df603d8cc2c72d55e32fff71 https://doi.org/10.1016/s0040-4039(01)92501-8 Zobrazit plný text záznamu