Human Endometrial Stromal Cells and Decidual Cells Express Cluster of Differentiation (CD) 13 Antigen/Aminopeptidase N and CD1O Antigen/Neutral Endopeptidase1
| Autor: | K. Takakura, Norihiko Okamoto, Masatoshi Kariya, Michiyuki Maeda, Hideharu Kanzaki, Kimitoshi Imai, T. Mori, Hiroshi Fujiwara, N. Emi |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
medicine.medical_specialty
CD40 Stromal cell biology Cluster of differentiation medicine.drug_class Decidua CD1 Cell Biology General Medicine Monoclonal antibody Molecular biology medicine.anatomical_structure Endocrinology Reproductive Medicine Antigen Internal medicine biology.protein medicine Decidual cells |
| Zdroj: | Biology of Reproduction. 46:328-334 |
| ISSN: | 1529-7268 0006-3363 |
| DOI: | 10.1095/biolreprod46.3.328 |
| Popis: | With specific monoclonal antibodies, we found that human endomethal stromal cells and decidual cells express two functionrelated surface antigens. Indirect immunofluorescence staining revealed that both endometrial stromal cells and decidual cells during the first trimester of pregnancy expressed cluster of differentiation (CD) 13 antigen and CD1O antigen, which are identical to aminopeptidase N and neutral endopeptidase, respectively. By flow cytometric analysis, CD1 3 antigen was detected on 8293% of the examined cells, and CD1O antigen was detected on 75-93% of the examined cells in endometrial stromal cellenriched preparations. Furthermore, peptidase activity was detected in these cell preparations by an assay based on the hydrolysis of alanine-p-nitroanilide into p-nitroaniline and alanine. |
| Databáze: | OpenAIRE |
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