Synthesis of Nanostructured Mixed-Valence Fe(II,III) Metal-Organic Framework and Its Application in Electrochemical Sensing of Amoxicillin
| Autor: | Thi Kim Ngan Nguyen, Tien Hung Nguyen, Manh B. Nguyen, Hoang Anh Nguyen, Thi Thu Ha Vu, Quoc Hung Le, Quang Hai Tran, Thi Hai Yen Pham |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of The Electrochemical Society. 170:056505 |
| ISSN: | 1945-7111 0013-4651 |
| DOI: | 10.1149/1945-7111/acced6 |
| Popis: | The study reports the development of a nanostructured mixed-valence Fe(II)Fe(III)BTC metal-organic framework (BTC = 1, 3, 5-benzenetricarboxylate) modified carbon paste electrode as a novel sensor for the amoxicillin detection in aqueous solutions using square wave voltammetry. The physicochemical properties of FeBTC were characterized using X-ray diffraction spectroscopy, Fourier-transform infrared spectroscopy, Brunauer–Emmett–Teller analysis, electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy. These techniques revealed that FeBTC has a surface area of 1211 m2 g−1, a total pore volume of 1.46 cm3 g−1, particle sizes ranging from 10 to 20 nm, and a mixed-valence structure. Furthermore, SEM, TEM, and energy-dispersive X-ray spectroscopy exhibited the homogeneous distribution of FeBTC throughout the modified electrode. The electrochemical study showed that the mixed-valence FeBTC improved the electron transfer capabilities of the electrode. Under optimal conditions, the modified electrode exhibited a significant increase in peak height compared to the unmodified electrode (4.6 times higher), with an acceptable reproducibility of 4.88% relative standard deviation. The linear range of the sensor was 1–100 μM with a good coefficient of determination of 0.9985, and a detection limit of 0.107 μM. Additionally, the sensor demonstrated excellent performance with the satisfactory recoveries and a good correlation with LC-MS/MS analysis. |
| Databáze: | OpenAIRE |
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