Synthesis of D-seco-13α-Androst-5-ene Derivatives

Autor:	Ágota Szájli, Mónika Gáspár, János Wölfling, Gyula Schneider, László Vörös
Rok vydání:	2006
Předmět:	Steric effects Grob fragmentation Chemistry Stereochemistry Synthon General Chemistry Formyl group Chirality (chemistry) Ene reaction
Zdroj:	Monatshefte für Chemie - Chemical Monthly. 137:1099-1107
ISSN:	1434-4475 0026-9247
DOI:	10.1007/s00706-005-0500-y
Popis:	3β-Hydroxy-16,17-seco-13α-androsta-5,16-dien-17-al was obtained from 3β-acetoxyandrost-5-en-17-one in six steps with a Grob fragmentation as the key step. This seco-steroid, containing a formyl group and an unsaturated side-chain in a sterically favourable cis position, is a useful synthon for the synthesis of novel heterocycles condensed to the 3β-hydroxy-13α-androst-5-en-17-one skeleton.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6d1e1a223e7fd06bb9003c20ed1457d1 https://doi.org/10.1007/s00706-005-0500-y Zobrazit plný text záznamu Full text from SpringerLink