PRELIMINARY INVESTIGATION BY RAMAN SPECTROSCOPY OF SOME POLYMERIC MATRIX WITH PHARMACEUTICAL APPLICATIONS
| Autor: | E. Dinte, M. Todica, Cosmin Farcau, Simion Astilean, C. V. Pop |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
chemistry.chemical_classification
Materials science Aqueous solution Ethylene oxide Clotrimazole technology industry and agriculture Polymeric matrix Statistical and Nonlinear Physics macromolecular substances Polymer Reversible process Condensed Matter Physics symbols.namesake chemistry.chemical_compound chemistry Chemical engineering medicine symbols Raman spectroscopy medicine.drug |
| Zdroj: | Modern Physics Letters B. 21:987-995 |
| ISSN: | 1793-6640 0217-9849 |
| DOI: | 10.1142/s0217984907013481 |
| Popis: | The possibility to use poly(ethylene oxide) as a polymeric matrix for some pharmaceutical products was analyzed. The behavior of the polymer in the aqueous solutions and the possible interactions between the polymer and the clotrimazole were investigated by Raman spectroscopy. Repeated action of the water on the polymeric conformation is a reversible process and the introduction of the clotrimazole in the polymeric gel do not modify the properties of the active substance of the pharmaceutical product. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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