Abstract 17473: Obesity is Associated With Impaired Left Atrial Function in Young Patients With Recent Onset Atrial Fibrillation

Autor: Dinant N Oemrawsingh, Rob A Vermond, Ernaldo G Marcos, Anne H Hobbelt, Yoran M Hummel, Joost P van Melle, Yuri Blaauw, Isabelle C van Gelder, Michiel Rienstra
Rok vydání: 2015
Předmět:
Zdroj: Circulation. 132
ISSN: 1524-4539
0009-7322
DOI: 10.1161/circ.132.suppl_3.17473
Popis: Introduction: Obesity is a risk factor for atrial fibrillation (AF), and reduction of weight has been shown to reduce the burden of AF. However, the exact underlying pathogenesis is unknown. Hypothesis: We hypothesize that obesity is related with impaired left atrial function, measured with echocardiographic strain analysis, in young patients ( Methods: We studied 94 patients of the Phenotyping young-onset AF patients study, all with sinus rhythm during echocardiography. Detailed clinical and echocardiographic information was collected. Three strain-patterns (reservoir, activation, and conduit strain) representing left atrial functional phases were measured. Results: Of the 94 patients, 32 were obese and 62 were non-obese (34±3 kg/m2 vs. 25±2 kg/m2, p Conclusions: In young patients with recent onset AF, obesity is associated with impaired left atrial function, in absence of dilatation. Left atrial dysfunction may be the first sign of atrial remodeling in obese AF patients.
Databáze: OpenAIRE