NONNUTRITIVE SUCKINO(NNS) DOES NOT STIMULATE THE SECRETION OF LIN6UAL AND GASTRIC LIPASES IN PREMATURE INFANTS

Autor:	Susan D Bowers, Paul Hamosh, Maroit Hamosh, Carla H York, Christine J Waring, Carol S Fink, Yolande F Smith, Judy Bernbaum
Rok vydání:	1987
Předmět:	medicine.medical_specialty business.industry medicine.disease Cystic fibrosis Postnatal age Low birth weight Endocrinology Internal medicine Pediatrics Perinatology and Child Health Hospital discharge Medicine Secretion medicine.symptom business Digestion Weight gain
Zdroj:	Pediatric Research. 21:278A-278A
ISSN:	1530-0447 0031-3998
DOI:	10.1203/00006450-198704010-00663
Popis:	NNS improves weight gain and allows earlier hospital discharge of low birth weight (LBW) infants (Pediatrics 71:41, 1983). The improved weight gain could be due to more efficient nutrient digestion and absprption. Preduodenal lipases have a compensatory function in fat digestion during physiologic (developmental) or pathologic (cystic fibrosis, alchoholism related) pancreatic insufficiency (J Clin Invest 67:838, 1981; 73:374, 1984; Padietr Res 18:402, 1984 and Gestroenterol 1987, in press). We have therefore investigated whether NNS stimulates the secretion of these lipases in LBW infants. Two separate studies were conducted: 1) 9 infants (gest. age 30.5±0.8 wks, postnatal age 29±3 days) received gavage feeding (GF) with and without NNS, each infant being his/her own control. 2) 10 infants (gest. age 29.7±0.8 wks, postnatal age 32±5 days) were divided into two groups: 4 infants received GF without NNS and 6 infants received GF with NNS. Lipase activity was measured in gastric aspirates. These data suggest, that increased secretion of lipases is not the cause of improved weight gain in infants fed by gavage with nonnutritive sucking. (Support: NIH grant HD 10823.)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6cdd804f7d3bdd603f1cb1c1d0abc165 https://doi.org/10.1203/00006450-198704010-00663 Zobrazit plný text záznamu