| Popis: |
The process of lymphocyte activation which leads to proliferation is involved in the majority of immunological events. Although the early metabolic changes in response to specific antigens or mitogenic lectins are well studied, the mechanism, however, is not yet completely understood. The increase in cell size is the first morphological change that we can observe, because the cell diameter more than doubles. This increase is followed by the enhancement of the synthesis of membrane phospholipids and by the change in their fatty acid composition implicated deacylation-reacylation reaction (Shinitzky M.). |
