ChemInform Abstract: Domino Reaction of 2,2-Dihydroxyindene-1,3-dione with Aromatic Amines: Efficient Synthesis of Isochromeno[4,3-b]indol-5(11H)-one Derivatives

Autor:	Shu-Jiang Tu, Mu-Yan Sun, Yi-Jing Dang, Fu-Jie Zhao, Xiao-Yan Meng, Bo Jiang
Rok vydání:	2015
Předmět:	Cascade reaction Organic reaction Chemistry Yield (chemistry) Microwave irradiation Organic chemistry Regioselectivity General Medicine
Zdroj:	ChemInform. 46
ISSN:	0931-7597
DOI:	10.1002/chin.201520162
Popis:	An efficient approach to 16 examples of polyfunctionalized isochromeno[4,3-b]indol-5(1H)-one derivatives, obtained in 60–85% yield and with excellent regioselectivity, has been developed through a domino reaction of 2,2-dihydroxyindene-1,3-dione with aromatic amines under microwave irradiation. The atom- and step-economy and scope make this reaction a powerful tool for assembling polyheterocyclic scaffolds of general chemical and biomedical interest.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6cb654e4a28edfe29ca383fe764c7b59 https://doi.org/10.1002/chin.201520162 Zobrazit plný text záznamu Plný text