Synthesis of nitrogen-containing heterocyclic compounds using perfluoro-2-methylpent-2-ene and perfluoro-5-azanon-4-ene

Autor:	Ki-Whan Chi, Yurii V. Gatilov, Irina Yu. Bagryanskay, Eduard L. Zhuzhgov, Georgii G. Furin
Rok vydání:	2000
Předmět:	Denticity Pyrimidine Hydrochloride Organic Chemistry Biochemistry Medicinal chemistry Inorganic Chemistry chemistry.chemical_compound chemistry Nucleophile Urea Environmental Chemistry Physical and Theoretical Chemistry Guanidine Ene reaction Triazine
Zdroj:	Journal of Fluorine Chemistry. 103:105-115
ISSN:	0022-1139
DOI:	10.1016/s0022-1139(99)00310-3
Popis:	Reactions of perfluoro-2-methylpent-2-ena or perfluoro-5-azanon-4-ene with a range of bidentate nitrogen nucleophiles (urea, acet-, benz-, 4-nitrobenz-amidine hydrochloride, 2-aminopyridine, 2-aminobenzimidazole, guanidine) in the presence of Et 3 N or KOH effectively provided partially fluorinated heterocycles of pyrimidine, 2H-pyrido[1,2-a]pyrimidine and [1,3,5]triazine derivatives. The structure of 2-pentafluoroethyl-3-trifluoromethyl-pyrido[1,2-a]pyrimidin-4-one was further confirmed by the X-ray crystallographic analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6c9b7dc32948571b88307f722ba11cab https://doi.org/10.1016/s0022-1139(99)00310-3 Zobrazit plný text záznamu Full Text from ScienceDirect