| Autor: |
M. Ferrari, M. Bresaola, Stefano Petrini, G. M. De Mia, G. Perugini, F. Ciuti, V. Silenzi, M. Paniccià, M. Fortunati |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Trends in Veterinary Sciences ISBN: 9783642364877 |
| DOI: |
10.1007/978-3-642-36488-4_12 |
| Popis: |
Currently, few information is available on the stimulation of neutralizing antibodies (NA) to porcine circovirus type 2 (PCV2). The aim of the present study was to characterize the humoral response, particularly the production of NA in pigs inoculated with an inactivated vaccine against PCV2. Twenty-five conventional pigs, seronegative to PCV2, were divided into two groups. Group 1 was composed of 14 animals that were injected by intramuscular route with 1 ml of inactivated vaccine. Group 2 was composed of 11 pigs and was used as a negative control. ELISA antibodies and NA were evaluated and a virological investigation was performed. The vaccine did not induce any clinical signs in immunized pigs. The animals in Group 1 developed IgG antibodies, detected by ELISA tests, between 14 and 42 post-vaccination days (PVD). In the same group, NA were produced between 35 and 42 PVD. In Group 2, neither ELISA antibodies nor NA were produced. No virus was isolated from any of the pigs during the experimental period. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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