The selective functionalization of saturated hydrocarbons. Part 47. Investigation of the size of the reagent involved in the FeII–FeIV manifold

Autor:	Franck Launay, Derek H. R. Barton
Rok vydání:	1998
Předmět:	inorganic chemicals Steric effects Cyclohexane Ligand Organic Chemistry Substrate (chemistry) Picolinic acid Photochemistry Biochemistry chemistry.chemical_compound chemistry Reagent Drug Discovery Surface modification Hydroxyl radical
Zdroj:	Tetrahedron. 54:12699-12706
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(98)00785-6
Popis:	Competition experiments between cyclohexane and various aromatic substrates have been carried out in pyridine-acetonitrile in order to ascertain the steric requirements of the FeII-H2O2 reagent in comparison with the FeIII-H2O2 reagent already studied. The latter is distinctly larger and much less reactive than the former. Although these results might indicate that the FeII-H2O2 reagent is simply the hydroxyl radical, the chemistry observed is strictly dependent on the presence of picolinic acid. Without the latter, no significant oxidation of any substrate is observed. Hydroxyl radical formation (Fenton Chemistry) is not considered to be ligand dependent in preceding investigations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6c87a260b7b528a82b1c7c99ed195b8b https://doi.org/10.1016/s0040-4020(98)00785-6 Zobrazit plný text záznamu Full Text from ScienceDirect