THERAPEUTIC HOTLINE: Primary cutaneous CD4 + small/medium-sized pleomorphic T cell lymphoma coexisting with myelodysplastic syndrome transforming into chronic myelomonocytic leukemia successfully treated with cyclophosphamide
| Autor: | Gra yna Chodorowska, Jana Hercogová, Ewa Dybiec, Aldona Pietrzak, Danuta Skomra, Bartłomiej Wawrzycki, Iwona Jazienicka, Małgorzata Kowal |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Chemotherapy
Pathology medicine.medical_specialty Mycosis fungoides Cyclophosphamide CD30 business.industry T cell medicine.medical_treatment Cancer Chronic myelomonocytic leukemia Dermatology General Medicine medicine.disease medicine.anatomical_structure hemic and lymphatic diseases medicine T-cell lymphoma business medicine.drug |
| Zdroj: | Dermatologic Therapy. 23:676-681 |
| ISSN: | 1396-0296 |
| Popis: | Cutaneous T cell lymphomas other than mycosis fungoides, Sezary syndrome, and primary cutaneous CD30+ lymphoproliferations constitute less than 10% of all cutaneous T cell lymphomas. Primary cutaneous small/medium CD4+ T cell lymphoma is a member of this third group of cutaneous lymphomas, separated out as provisional entity in the World Health Organization classification – European Organization for Research and Treatment of Cancer (WHO-EORTC) classification. It still awaits development of more precise diagnostic criteria and optimal therapy. We report a case of primary cutaneous CD4 + small/medium-sized pleomorphic T cell lymphoma accompanied with myelodysplastic syndrome successfully treated with cyclophosphamide. It seems that cyclophosphamide as a single-agent chemotherapy in patients with disseminated lesions might be safe and quite effective therapeutic option. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|