Solubilities of theobromine and caffeine in supercritical carbon dioxide: correlation with density-based models
| Autor: | Stanley Hartland, G.S. Varadarajan, Shufen Li |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Supercritical carbon dioxide
General Chemical Engineering General Physics and Astronomy Thermodynamics chemistry.chemical_compound Density based chemistry Carbon dioxide medicine Organic chemistry Physical and Theoretical Chemistry Solubility Caffeine Theobromine Order of magnitude Bar (unit) medicine.drug |
| Zdroj: | Fluid Phase Equilibria. 68:263-280 |
| ISSN: | 0378-3812 |
| DOI: | 10.1016/0378-3812(91)85023-n |
| Popis: | Li S., Varadarajan G.S. and Hartland S., 1991. Solubilities of theobromine and caffeine in supercritical carbon dioxide: correlation with density-based models. Fluid Phase Equilibria 68: 263-280. Solubilities of theobromine and caffeine in supercritical carbon dioxide at several different temperatures (40, 60, 80 and 95°C) and pressures from 80 to 300 bar were measured using a dynamic method. The solubilities of theobromine were two orders of magnitude less than those of caffeine even though both compounds are xanthines with very similar chemical structures. The reasons are considered from a thermodynamic viewpoint. The applicability and limitations of three density-based models used to correlate the data are discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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