ChemInform Abstract: Synthesis, Design and Biological Evaluation of Novel Highly Potent Tacrine Congeners for the Treatment of Alzheimer′s Disease

Autor:	Slavka Hamulakova, Martina Hrabinova, Ján Imrich, Pavol Kristian, Kamil Kuca, Ladislav Janovec, Maria Banasova
Rok vydání:	2013
Předmět:	chemistry.chemical_compound chemistry Tacrine medicine Acridine derivatives General Medicine Selectivity Combinatorial chemistry Derivative (chemistry) Biological evaluation medicine.drug
Zdroj:	ChemInform. 44
ISSN:	0931-7597
Popis:	Among all the tacrine congeners synthesized, derivative (III) shows the best activity and selectivity against hAChE and derivative (Id) against hBChE.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6c71669152b0f30ed8ba18628176a9c9 https://doi.org/10.1002/chin.201304128 Zobrazit plný text záznamu Plný text