Ten-Year Mortality after Community-acquired Pneumonia. A Prospective Cohort

Autor: Sumit R. Majumdar, Dean T. Eurich, Jasjeet K. Minhas-Sandhu, Thomas J. Marrie
Rok vydání: 2015
Předmět:
Zdroj: American Journal of Respiratory and Critical Care Medicine. 192:597-604
ISSN: 1535-4970
1073-449X
DOI: 10.1164/rccm.201501-0140oc
Popis: Rationale: Information on the long-term prognosis after community-acquired pneumonia (CAP) is limited.Objectives: To determine if CAP increases adverse long-term outcomes relative to a control population.Methods: Between 2000 and 2002, 6,078 adults with CAP from six hospitals and seven emergency departments in Edmonton (AB, Canada) were prospectively recruited and matched on age, sex, and site of treatment with five control subjects without pneumonia (n = 29,402). Mortality, hospitalizations, and emergency department admissions through 2012 were evaluated using multivariable Cox proportional hazards analyses adjusted for socioeconomic status and comorbidities.Measurements and Main Results: Average age was 59 years (2,682 [44%] ≥ 65 yr), 3,214 (53%) were men, and 3,425 (56%) were managed as outpatients. Over a median of 9.8 years, 2,858 patients with CAP died compared with 9,399 control subjects (absolute risk difference, 30 per 1,000 patient years [py]; adjusted hazard ratio [aHR], 1.65; 95% confidence in...
Databáze: OpenAIRE