Microspheres - A New Drug Delivery System: A Review
| Autor: | P. S. Patil, L. V. Kulkarni, G.S. Bamane ., C. M. Kumbhar, P. A. Jadhav, V. B. Metkari |
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| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Journal of Current Pharma Research. 4:1128-1133 |
| ISSN: | 2230-7842 2230-7834 |
| DOI: | 10.33786/jcpr.2014.v04i02.003 |
| Popis: | Microspheres are normally free flowing powders consisting of proteins or synthetic polymers which are biodegradable in nature and preferably having a particle size less than 200-500 µm. The range of techniques for the preparation of microspheres offers a Variety of opportunities to control aspects of drug administration and enhance the therapeutic efficacy of a given drug. There are different approaches in delivering a therapeutic substance to the target site in a sustained controlled release manner. One such approach is using microspheres as carriers for drugs also known as micro particles. It is the reliable means to deliver the drug to the target site with specificity, if customized, and to maintain the desired concentration at the site of significance. Microspheres established much attention not only for extended release, but also for targeting of anticancer drugs. In future by combining various other strategies, microspheres will find the central place in new drug delivery, particularly in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted and effective in vivo delivery and supplements as miniature versions of diseased organ and tissues in the body. |
| Databáze: | OpenAIRE |
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