Synthesis and Biological Activity of 4,5,6,7-Tetrahydro-2H-indazole Derivatives

Autor:	V. L. Gein, I. P. Rudakova, E. B. Levandovskaya, V. V. Novikova, N. V. Nosova, A. N. Yankin
Rok vydání:	2019
Předmět:	Indazole 010405 organic chemistry Chemistry Hydrazine Biological activity General Chemistry 010402 general chemistry Antimicrobial 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Organic chemistry Hydrate Phenylhydrazine
Zdroj:	Russian Journal of General Chemistry. 89:1169-1176
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363219060112
Popis:	Novel 4,5,6,7-tetrahydro-2H-indazole derivatives were obtained via the reaction of N1,N3,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides with hydrazine hydrate. The reaction of 4-oxocyclo-hexane-1,3-dicarboxamides with phenylhydrazine led to the formation of hydrazones instead of indazoles. The synthesized compounds were tested for antimicrobial, analgesic and anti-inflammatory activities
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6c23bcc24b82b110ba4a0f466dd6e0a7 https://doi.org/10.1134/s1070363219060112 Zobrazit plný text záznamu Plný text ve formátu PDF