Secondary Metabolites by Chemical Screening 14. Transformation of Elaiophylin in subunits of Naturally Occurring Acid Ionophores: Synthesis, Anticoccidial Activity and Studies Concerning the Ionophoric Properties

Autor:	Gerhard Kretzschmar, Peter Dr. Hammann, Frank Ditzel, Wolfgang Raether, Achim Kröger, Mária Kajtár-Peredy, Robert Dr Klein
Rok vydání:	1991
Předmět:	Pharmacology Stereochemistry Chemistry Organic Chemistry Acetal Nuclear magnetic resonance spectroscopy Nuclear Overhauser effect Analytical Chemistry Chemical screening Elaiophylin NMR spectra database Transformation (genetics) chemistry.chemical_compound Biological property
Zdroj:	HETEROCYCLES. 32:1471
ISSN:	0385-5414
DOI:	10.3987/com-91-5778
Popis:	The synthesis of the polyether subunits (8-11), starting from elaiophylin (1), as well as their biological properties, nmr spectra and conformational studies were described and discussed. Based upon the missing ability of potassium transport it was deduced that compounds (8-11) were new lead structures concerning their anticoccidial activity
Databáze:	OpenAIRE
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